The main drugs used to combat agricultural pests, and urban health pests. Using historical long-term, large amount of variety. In the twentieth century, the rapid Developing of agriculture, pesticides make agricultural production soared. Few traditional agents, such as mineral oil emulsion mechanism in surface physics insecticidal effect, while the vast majority of organic synthetic pesticides into the insect body, interfere with or disrupt the normal physiology in certain parts of the biochemical reactions. Way into the insect body, some with feeding mouthparts into the digestive tract, penetrate into the blood, either through the skin, and some also through the stoma and trachea, Pharmacy and pests in vivo into the body enzymes biochemical reactions, some reactions Pharmacy degradation lost virulence, but some agents are activated so that the enhanced virulence, is not degradable compounds (or activated) Pharmacy because of the role of different mechanisms of cytotoxicity in certain parts of the play, such as acting on the nervous system, or the role of breathing intracellular metabolic processes.